Dynamics of the formation of a hydrogel by a pathogenic amyloid peptide: islet amyloid polypeptide

Many chronic degenerative diseases result from aggregation of misfolded polypeptides to form amyloids. Many amyloidogenic polypeptides are surfactants and their assembly can be catalysed by hydrophobic-hydrophilic interfaces (an air-water interface in-vitro or membranes in-vivo). We recently demonst...

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Bibliographic Details
Main Authors: Vaux, D, Jean, L, Lee, C, Hodder, P, Hawkins, N
Format: Journal article
Published: Nature Publishing Group 2016