Opiate modulation of the pituitary-adrenal axis: effects of stress and circadian rhythm.

Opiate modulation of the pituitary-adrenal axis: effects of stress and circadian rhythm.

The opiate control of the pituitary-adrenal axis has been investigated in normal subjects. The infusion of 1 mg of the met-enkephalin analogue, DAMME, led to a fall in circulating cortisol in spite of a fall in blood pressure. Conversley, 16 mg of the opiate antagonist, naloxone led to brisk and pro...

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Bibliographic Details
Main Authors:	Grossman, A, Gaillard, R, McCartney, P, Rees, L, Besser, G
Format:	Journal article
Language:	English
Published:	1982

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