Genomic alterations underlie a pan-cancer metabolic shift associated with tumour hypoxia

Genomic alterations underlie a pan-cancer metabolic shift associated with tumour hypoxia

Altered metabolism is a hallmark of cancer. However, the role of genomic changes in metabolic genes driving the tumour metabolic shift remains to be elucidated. Here, we have investigated the genomic and transcriptomic changes underlying this shift across ten different cancer types.A systematic pan-...

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Autors principals:	Haider, S, McIntyre, A, van Stiphout, R, Winchester, L, Wigfield, S, Harris, A, Buffa, F
Format:	Journal article
Idioma:	English
Publicat:	BioMed Central 2016

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