Genomic alterations underlie a pan-cancer metabolic shift associated with tumour hypoxia
Altered metabolism is a hallmark of cancer. However, the role of genomic changes in metabolic genes driving the tumour metabolic shift remains to be elucidated. Here, we have investigated the genomic and transcriptomic changes underlying this shift across ten different cancer types.A systematic pan-...
Những tác giả chính: | Haider, S, McIntyre, A, van Stiphout, R, Winchester, L, Wigfield, S, Harris, A, Buffa, F |
---|---|
Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
BioMed Central
2016
|
Những quyển sách tương tự
-
The tumour hypoxia induced non-coding transcriptome.
Bằng: Choudhry, H, et al.
Được phát hành: (2016) -
Gene expression signatures as biomarkers of tumour hypoxia
Bằng: Harris, B, et al.
Được phát hành: (2015) -
Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis.
Bằng: Jubb, A, et al.
Được phát hành: (2010) -
The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer (TNBC)
Bằng: Harris, A, et al.
Được phát hành: (2016) -
Metabolic Shift and Hyperosmolarity Underlie Age-Related Macular Degeneration
Bằng: Laurent Schwartz, et al.
Được phát hành: (2024-09-01)