Molecular mechanism by which CD244 negatively regulates the immune response

Eitemau Tebyg

• Direct and indirect interactions of the cytoplasmic region of CD244 (2B4) in mice and humans with FYN kinase.
  gan: Clarkson, N, et al.
  Cyhoeddwyd: (2007)
• CD2 and CD244: paired receptors
  gan: Brown, M, et al.
  Cyhoeddwyd: (2008)
• CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76.
  gan: Hassan, N, et al.
  Cyhoeddwyd: (2006)
• Inhibition and activation by CD244 depends on CD2 and phospholipase C-gamma1.
  gan: Clarkson, N, et al.
  Cyhoeddwyd: (2009)
• CD6 Regulates T-Cell Responses through Activation-Dependent Recruitment of the Positive Regulator SLP-76 (vol 26, pg 6727, 2006)
  gan: Hassan, N, et al.
  Cyhoeddwyd: (2009)