Vps35-dependent recycling of Trem2 regulates microglial function

Triggering receptor expressed on myeloid cells 2 (Trem2), an immune-modulatory receptor, is preferentially expressed in microglia of central nervous system. Trem2 might be involved in the development of Alzheimer's disease (AD) through regulating the inflammatory responses and phagocytosis of m...

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Bibliographic Details
Main Authors: Yin, J, Liu, X, He, Q, Zhou, L, Yuan, Z, Zhao, S
Format: Journal article
Published: John Wiley & Sons 2016