Expression of aberrant HLA-B27 molecules is dependent on B27 dosage and peptide supply.

Expression of aberrant HLA-B27 molecules is dependent on B27 dosage and peptide supply.

OBJECTIVES: Cellular expression of non-classical forms of human leukocyte antigen (HLA)-B27 (NC-B27) may be involved in spondyloarthritis (SpA) pathogenesis. We used a novel B27-specific monoclonal antibody, HD6, to ask if B27 transgenic (TG) rat splenocytes express these NC-B27 molecules. We also i...

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Détails bibliographiques
Auteurs principaux: McHugh, K, Rysnik, O, Kollnberger, S, Shaw, J, Utriainen, L, Al-Mossawi, H, Payeli, S, Marroquin, O, Milling, S, Renner, C, Bowness, P
Format: Journal article
Langue:English
Publié: 2014

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