Reciprocal interactions between circadian clocks and aging.

Virtually, all biological processes in the body are modulated by an internal circadian clock which optimizes physiological and behavioral performance according to the changing demands of the external 24-h world. This circadian clock undergoes a number of age-related changes, at both the physiologica...

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Main Authors: Banks, G, Nolan, P, Peirson, S
Format: Journal article
Language:English
Published: Springer 2016
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author Banks, G
Nolan, P
Peirson, S
author_facet Banks, G
Nolan, P
Peirson, S
author_sort Banks, G
collection OXFORD
description Virtually, all biological processes in the body are modulated by an internal circadian clock which optimizes physiological and behavioral performance according to the changing demands of the external 24-h world. This circadian clock undergoes a number of age-related changes, at both the physiological and molecular levels. While these changes have been considered to be part of the normal aging process, there is increasing evidence that disruptions to the circadian system can substantially impact upon aging and these impacts will have clear health implications. Here we review the current data of how both the physiological and core molecular clocks change with age and how feedback from external cues may modulate the aging of the circadian system.
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spelling oxford-uuid:6f5a663d-91be-48f2-87a1-def6cac3b2932022-03-26T19:30:12ZReciprocal interactions between circadian clocks and aging.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:6f5a663d-91be-48f2-87a1-def6cac3b293EnglishSymplectic Elements at OxfordSpringer2016Banks, GNolan, PPeirson, SVirtually, all biological processes in the body are modulated by an internal circadian clock which optimizes physiological and behavioral performance according to the changing demands of the external 24-h world. This circadian clock undergoes a number of age-related changes, at both the physiological and molecular levels. While these changes have been considered to be part of the normal aging process, there is increasing evidence that disruptions to the circadian system can substantially impact upon aging and these impacts will have clear health implications. Here we review the current data of how both the physiological and core molecular clocks change with age and how feedback from external cues may modulate the aging of the circadian system.
spellingShingle Banks, G
Nolan, P
Peirson, S
Reciprocal interactions between circadian clocks and aging.
title Reciprocal interactions between circadian clocks and aging.
title_full Reciprocal interactions between circadian clocks and aging.
title_fullStr Reciprocal interactions between circadian clocks and aging.
title_full_unstemmed Reciprocal interactions between circadian clocks and aging.
title_short Reciprocal interactions between circadian clocks and aging.
title_sort reciprocal interactions between circadian clocks and aging
work_keys_str_mv AT banksg reciprocalinteractionsbetweencircadianclocksandaging
AT nolanp reciprocalinteractionsbetweencircadianclocksandaging
AT peirsons reciprocalinteractionsbetweencircadianclocksandaging