Total synthesis of spirastrellolide A methyl ester--part 2: Subunit union and completion of the synthesis.
(Figure Presented) Succumbing to synthesis: The stereocontrolled total synthesis of spirastrellolide A methyl ester is reported. The union of two key C1-C16 and C17-C40 subunits is followed by macrolactonization and late-stage side chain attachment by a cross-metathesis reaction anda π-allyl Stille...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2008
|