Quenching protein dynamics interferes with HIV capsid maturation.

Quenching protein dynamics interferes with HIV capsid maturation.

Maturation of HIV-1 particles encompasses a complex morphological transformation of Gag via an orchestrated series of proteolytic cleavage events. A longstanding question concerns the structure of the C-terminal region of CA and the peptide SP1 (CA-SP1), which represents an intermediate during matur...

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Bibliographic Details
Main Authors: Wang, M, Quinn, CM, Perilla, JR, Zhang, H, Shirra, R, Hou, G, Byeon, I-J, Suiter, CL, Ablan, S, Urano, E, Nitz, TJ, Aiken, C, Freed, EO, Zhang, P, Schulten, K, Gronenborn, AM, Polenova, T
Format: Journal article
Language:English
Published: Nature Publishing Group 2017

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