A mass action model of a fibroblast growth factor signaling pathway and its simplification
We consider a kinetic law of mass action model for Fibroblast Growth Factor (FGF) signaling, focusing on the induction of the RAS-MAP kinase pathway via GRB2 binding. Our biologically simple model suffers a combinatorial explosion in the number of differential equations required to simulate the syst...
| Asıl Yazarlar: | , , |
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| Materyal Türü: | Journal article |
| Baskı/Yayın Bilgisi: |
Springer
2008
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