The effect of alpha-synuclein knockdown on MPP+ toxicity in models of human neurons.

The effect of alpha-synuclein knockdown on MPP+ toxicity in models of human neurons.

The protein alpha-synuclein is central to the pathophysiology of Parkinson's disease (PD) but its role in the development of neurodegeneration remains unclear. alpha-Synuclein-knockout mice develop without gross abnormality and are resistant to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP...

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Bibliographic Details
Main Authors:	Fountaine, T, Venda, L, Warrick, N, Christian, H, Brundin, P, Channon, K, Wade-Martins, R
Format:	Journal article
Language:	English
Published:	2008

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