Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha.

OBJECTIVE: To evaluate the safety and efficacy of a chimeric monoclonal antibody to tumor necrosis factor alpha (TNF alpha) in the treatment of patients with rheumatoid arthritis (RA). METHODS: Twenty patients with active RA were treated with 20 mg/kg of anti-TNF alpha in an open phase I/II trial la...

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Váldodahkkit: Elliott, M, Maini, R, Feldmann, M, Long-Fox, A, Charles, P, Katsikis, P, Brennan, F, Walker, J, Bijl, H, Ghrayeb, J
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 1993

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