Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha.
OBJECTIVE: To evaluate the safety and efficacy of a chimeric monoclonal antibody to tumor necrosis factor alpha (TNF alpha) in the treatment of patients with rheumatoid arthritis (RA). METHODS: Twenty patients with active RA were treated with 20 mg/kg of anti-TNF alpha in an open phase I/II trial la...
Main Authors: | Elliott, M, Maini, R, Feldmann, M, Long-Fox, A, Charles, P, Katsikis, P, Brennan, F, Walker, J, Bijl, H, Ghrayeb, J |
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格式: | Journal article |
語言: | English |
出版: |
1993
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