Structure of human complement C8, a precursor to membrane attack.

Complement component C8 plays a pivotal role in the formation of the membrane attack complex (MAC), an important antibacterial immune effector. C8 initiates membrane penetration and coordinates MAC pore formation. High-resolution structures of C8 subunits have provided some insight into the function...

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Detalles Bibliográficos
Main Authors: Bubeck, D, Roversi, P, Donev, R, Morgan, B, Llorca, O, Lea, S
Formato: Journal article
Idioma:English
Publicado: 2011