The role of BET attenuation in melanoma

The role of BET attenuation in melanoma

Bromodomain and extra-terminal (BETs) proteins function as epigenetic readers by docking onto acetylated lysine residues (Kac) on histone tails via tandem bromodomains (BRDs), and recruiting protein binding partners via an extra-terminal recruitment domain (ET). Targeting BET BRDs is efficacious in...

Fuld beskrivelse

Bibliografiske detaljer
Hovedforfatter:	Henderson, EK
Andre forfattere:	Filippakopoulos, P
Format:	Thesis
Sprog:	English
Udgivet:	2020
Fag:	Melanoma p53 Cancer Skin cancer Prostate cancer BET proteins

Lignende værker

Impaired T cell proliferation by ex vivo BET-inhibition impedes adoptive immunotherapy in a murine melanoma model
af: Jonathan Chee, et al.
Udgivet: (2020-02-01)

Bydgoszcz universities students' awareness about melanoma
af: Katarzyna Mirończuk, et al.
Udgivet: (2017-08-01)

Bydgoszcz universities students' awareness about melanoma
af: Katarzyna Mirończuk, et al.
Udgivet: (2017-08-01)

Malignant melanoma and spina bifida
af: Sarah O'Mahony, et al.
Udgivet: (2024-09-01)

Co‐targeting BET and MEK as salvage therapy for MAPK and checkpoint inhibitor‐resistant melanoma
af: Ileabett M Echevarría‐Vargas, et al.
Udgivet: (2018-04-01)

Targeting BET Proteins Decreases Hyaluronidase-1 in Pancreatic Cancer
af: Krishan Kumar, et al.
Udgivet: (2023-05-01)

The MDM2 inhibitor CGM097 combined with the BET inhibitor OTX015 induces cell death and inhibits tumor growth in models of neuroblastoma
af: Tyler Maser, et al.
Udgivet: (2020-11-01)

The role of artificial intelligence in cancer diagnostics - a review
af: Paweł Stanicki, et al.
Udgivet: (2021-09-01)

A Comprehensive Review of BET Protein Biochemistry, Physiology, and Pathological Roles
af: Hafiz Akbar Ali, et al.
Udgivet: (2022-03-01)

Trends in incidence of non-melanoma and melanoma skin cancers in central Serbia
af: Antonijević Aleksandar, et al.
Udgivet: (2018-01-01)

Correlation of p53 immunoexpression with DNA ploidy and apoptotic index in subsets of prostate cancer: A marker reiterated in progression and recurrence of prostate cancer
af: Anju Bansal, et al.
Udgivet: (2015-01-01)

Determinants of problem sports betting among college students: moderating roles of betting frequency and impulsive betting tendency
af: Yawen Shen
Udgivet: (2023-10-01)

Hedging on Betting Markets
af: Gustav Axén, et al.
Udgivet: (2020-08-01)

Home bias in sport betting: Evidence from Czech betting market
af: Rostislav Staněk
Udgivet: (2017-03-01)

The role of SNPs in the management of cancer in the broader population
af: Kitchen-Smith, I
Udgivet: (2020)

High expression of Talin-1 is associated with tumor progression and recurrence in melanoma skin cancer patients
af: Yasaman Rezaie, et al.
Udgivet: (2023-04-01)

The BET degrader ZBC260 suppresses stemness and tumorigenesis and promotes differentiation in triple-negative breast cancer by disrupting inflammatory signaling
af: Deeksha Sharma, et al.
Udgivet: (2023-11-01)

Early Detection of Melanoma Skin Cancer
af: Faruk Alendar, et al.
Udgivet: (2009-02-01)

Exploring Melanoma Dynamics: Insights from a 3D Cell Culture Model with Vemurafenib Treatment
af: Tholstrup Rikke, et al.
Udgivet: (2024-01-01)

The emerging role of BET inhibitors in breast cancer
af: Angeliki Andrikopoulou, et al.
Udgivet: (2020-10-01)

Activity of BET-proteolysis targeting chimeric (PROTAC) compounds in triple negative breast cancer
af: María del Mar Noblejas-López, et al.
Udgivet: (2019-08-01)

Home bias in sport betting: Evidence from Czech betting market
af: Rostislav Staněk
Udgivet: (2017-03-01)

Not Your Mother’s Melanoma: Causes and Effects of Early Melanoma Diagnosis
af: Kaviyon Sadrolashrafi, et al.
Udgivet: (2022-11-01)

Cisplatin and Paclitaxel Modulated the Cell Survival Potential of Prostate Cancer Cells
af: Sina Kashani, et al.
Udgivet: (2020-01-01)

Higher Numbers of T-Bet+ Tumor-Infiltrating Lymphocytes Associate with Better Survival in Human Epithelial Ovarian Cancer
af: Yun Xu, et al.
Udgivet: (2017-01-01)

Cytotoxic Evaluation of Some Fused Pyridazino- and Pyrrolo-quinazolinones Derivatives on Melanoma and Prostate Cell Lines
af: Golnaz Vaseghi, et al.
Udgivet: (2017-01-01)

Diagnostic Accuracy and Safety of Teledermoscopy for Cutaneous Melanoma Triage in Northern Sweden
af: Virginia Zazo, et al.
Udgivet: (2024-02-01)

Immunogenicity of prostate cancer is augmented by BET bromodomain inhibition
af: Wendy Mao, et al.
Udgivet: (2019-10-01)

Epidemiological Manifestations and Risk Assessment of Melanoma and other Skin Cancers in Altaiskiy Krai
af: A. I. Blokh, et al.
Udgivet: (2018-10-01)

Effects of expertise on football betting
af: Khazaal Yasser, et al.
Udgivet: (2012-05-01)

Metformin: Focus on Melanoma
af: Emilie Jaune, et al.
Udgivet: (2018-08-01)

Morbidity of non-melanoma skin cancer
af: Antonijević Aleksandar, et al.
Udgivet: (2017-01-01)

Prostate Cancer and Li-Fraumeni Syndrome: Implications for Screening and Therapy
af: Colleen K. Spees, et al.
Udgivet: (2015-03-01)

PLASTIC RESTORATION OF A FACIAL DEFECT AFTER SURGICAL REMOVAL OF A LARGE MALIGNANT MELANOMA
af: Rosen B. TSOLOV
Udgivet: (2022-09-01)

Noninvasive Real-Time Automated Skin Lesion Analysis System for Melanoma Early Detection and Prevention
af: Omar Abuzaghleh, et al.
Udgivet: (2015-01-01)

Desmoplastic melanoma presenting as an alopecic patch in a young patient
af: Lauren C. LaMonica, MPH, et al.
Udgivet: (2023-08-01)

Epidemiological trends in skin cancer
af: Zoe Apalla, et al.
Udgivet: (2017-05-01)

Acral Lentiginous Melanoma of the Thumb: Dermoscopy and Treatment
af: Antonella Tammaro, et al.
Udgivet: (2023-09-01)

Dermoscopic Features of Amelanotic and Hypomelanotic Melanomas: A Review of 49 Cases
af: Sarah Dawood, et al.
Udgivet: (2022-05-01)

Editorial: New strategies for the treatment of advanced melanoma and non-melanoma skin cancer
af: Alessia Villani, et al.
Udgivet: (2024-01-01)