The role of BET attenuation in melanoma

The role of BET attenuation in melanoma

Bromodomain and extra-terminal (BETs) proteins function as epigenetic readers by docking onto acetylated lysine residues (Kac) on histone tails via tandem bromodomains (BRDs), and recruiting protein binding partners via an extra-terminal recruitment domain (ET). Targeting BET BRDs is efficacious in...

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Dettagli Bibliografici
Autore principale:	Henderson, EK
Altri autori:	Filippakopoulos, P
Natura:	Tesi
Lingua:	English
Pubblicazione:	2020
Soggetti:	Melanoma p53 Cancer Skin cancer Prostate cancer BET proteins

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