The role of BET attenuation in melanoma
Bromodomain and extra-terminal (BETs) proteins function as epigenetic readers by docking onto acetylated lysine residues (Kac) on histone tails via tandem bromodomains (BRDs), and recruiting protein binding partners via an extra-terminal recruitment domain (ET). Targeting BET BRDs is efficacious in...
1. autor: | Henderson, EK |
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Kolejni autorzy: | Filippakopoulos, P |
Format: | Praca dyplomowa |
Język: | English |
Wydane: |
2020
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Hasła przedmiotowe: |
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