Fibrillin-1 misfolding and disease.

Fibrillin-1 misfolding and disease.

Fibrillin-1 is a 350 kDa calcium-binding protein which assembles to form 10-12 nm microfibrils in the extracellular matrix (ECM). The structure of fibrillin-1 is dominated by two types of disulfide-rich motifs, the calcium- binding epidermal growth factor-like (cbEGF) and transforming growth factor...

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Bibliographic Details
Main Authors:	Whiteman, P, Hutchinson, S, Handford, P
Format:	Journal article
Language:	English
Published:	2006

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