The role of T cell receptor dimerization for T cell antagonism and T cell specificity.

T cell responses are highly specific and T cell receptors (TCRs) can recognise subtle differences in major histocompatibility complex (MHC)-peptide complexes. While nominal peptide antigens usually act as full agonists that trigger the whole spectrum of T cell responses, some peptides exhibiting mut...

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Bibliographic Details
Main Authors: Salzmann, M, Bachmann, M
Format: Journal article
Language:English
Published: 1998