Modern solutions for ancient pathogens: direct pathogen sequencing for diagnosis of lepromatous leprosy and cerebral coenurosis
Microbes unculturable in vitro remain diagnostically challenging, dependent historically on clinical findings, histology, or targeted molecular detection. We applied whole-genome sequencing directly from tissue to diagnose infections with mycobacteria (leprosy) and parasites (coenurosis). Direct pat...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
Oxford University Press
2022
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