Structure of the ribosomal oxygenase OGFOD1 provides insights into the regio- and stereoselectivity of prolyl hydroxylases
Post-translational ribosomal protein hydroxylation is catalyzed by 2-oxoglutarate (2OG) and ferrous iron dependent oxygenases, and occurs in prokaryotes and eukaryotes. OGFOD1 catalyzes trans-3 prolyl hydroxylation at Pro62 of the small ribosomal subunit protein uS12 (RPS23) and is conserved from ye...
Main Authors: | Horita, S, Scotti, J, Thinnes, C, Taromsari, Y, Thalhammer, A, Ge, W, Aik, W, Loenarz, C, Schofield, C, McDonough, M |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2015
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