Capsular typing method for Streptococcus agalactiae using whole genome sequence data

<p>Group B streptococcus (GBS) capsular serotype is a major determ inant of virulence, and affects potential vaccine coverage. Here we report a whole genome sequencing-based method for GBS serotype assignment. This shows high agree ment (kappa=0.92) with conventional methods, and...

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Bibliographic Details
Main Authors: Sheppard, A, Vaughan, A, Jones, N, Turner, P, Turner, C, Efstratiou, A, Patel, D, MMM Informatics Group, Walker, A, Berkley, J, Crook, D, Seale, A
Format: Journal article
Published: American Society for Microbiology 2016
Description
Summary:<p>Group B streptococcus (GBS) capsular serotype is a major determ inant of virulence, and affects potential vaccine coverage. Here we report a whole genome sequencing-based method for GBS serotype assignment. This shows high agree ment (kappa=0.92) with conventional methods, and increased serotype assignment (100%) to all ten capsular types.</p>