In vitro mechanism of action on insulin release of S-22068, a new putative antidiabetic compound.
1. The MIN6 cell line derived from in vivo immortalized insulin-secreting pancreatic beta cells was used to study the insulin-releasing capacity and the cellular mode of action of S-22068, a newly synthesized imidazoline compound known for its antidiabetic effect in vivo. 2. S-22068, was able to rel...
Main Authors: | Le Brigand, L, Virsolvy, A, Manechez, D, Godfroid, J, Guardiola-Lemaître, B, Gribble, F, Ashcroft, F, Bataille, D |
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Format: | Journal article |
Language: | English |
Published: |
1999
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