The pharmacogenetics of methotrexate in inflammatory bowel disease.

The pharmacogenetics of methotrexate in inflammatory bowel disease.

OBJECTIVES: Methotrexate (MTX) is an effective immunosuppressive treatment in inflammatory bowel disease (IBD) but its use is limited by unpredictable toxicity and efficacy. MTX metabolism is complex involving a number of enzymes. An individual's response to MTX may in part be genetically dete...

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Bibliographic Details
Main Authors:	Herrlinger, K, Cummings, JR, Barnardo, M, Schwab, M, Ahmad, T, Jewell, D
Format:	Journal article
Language:	English
Published:	2005

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