The mouse Runx1 +23 hematopoietic stem cell enhancer confers hematopoietic specificity to both Runx1 promoters.

The transcription factor Runx1 plays a pivotal role in hematopoietic stem cell (HSC) emergence, and studies into its transcriptional regulation should give insight into the critical steps of HSC specification. Recently, we identified the Runx1 +23 enhancer that targets reporter gene expression to th...

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Hlavní autoři: Bee, T, Ashley, E, Bickley, SR, Jarratt, A, Li, P, Sloane-Stanley, J, Göttgens, B, de Bruijn, M
Médium: Journal article
Jazyk:English
Vydáno: 2009