Sugar immunogens

Sugar immunogens

Disclosed are compositions and methods useful for inducing an immunogenic response in a subject or host. In particular, the compositions and methods may be directed to carbohydrate HIV vaccines and to methods of producing a carbohydrate HIV vaccine by introducing antigenic sugars into mimics of the...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Dwek, R, Scanlan, C, Dunlop, D, Mansab, F, Tully, S, Wentworth, P, Zitzmann, N
स्वरूप:	Patent
प्रकाशित:	World Intellectual Property Ogranization 2009

समान संसाधन

Exploiting the defensive sugars of HIV-1 for drug and vaccine design
द्वारा: Scanlan, C, और अन्य
प्रकाशित: (2007)

Yeast mannan genetics controls the molecular specificity of anti-carbohydrate antibodies cross-reactive to the HIV envelope
द्वारा: Dunlop, D, और अन्य
प्रकाशित: (2009)

P05-11. Yeast mannan genetics controls the molecular specificity of anti-carbohydrate antibodies cross-reactive to the HIV envelope
द्वारा: Dwek R, और अन्य
प्रकाशित: (2009-10-01)

Antigenic mimicry of the HIV envelope by AIDS-Associated pathogens
द्वारा: Dunlop, D, और अन्य
प्रकाशित: (2008)

Antigenic mimicry of the HIV envelope by AIDS-associated pathogens.
द्वारा: Dunlop, D, और अन्य
प्रकाशित: (2008)

Polysaccharide mimicry of the epitope of the broadly neutralizing anti-HIV antibody, 2G12, induces enhanced antibody responses to self oligomannose glycans.
द्वारा: Dunlop, D, और अन्य
प्रकाशित: (2010)

Emerging principles for the therapeutic exploitation of glycosylation.
द्वारा: Dalziel, M, और अन्य
प्रकाशित: (2014)

Liposome treatment of viral infections
द्वारा: Dwek, R, और अन्य
प्रकाशित: (2011)

Inhibition of mammalian glycan biosynthesis produces non-self antigens for a broadly neutralising, HIV-1 specific antibody.
द्वारा: Scanlan, C, और अन्य
प्रकाशित: (2007)

Imino sugar inhibitors for treating the lysosomal glycosphingolipidoses.
द्वारा: Butters, T, और अन्य
प्रकाशित: (2005)

Use of iminosugar derivatives to inhibit ion channel activity
द्वारा: Zitzmann, N, और अन्य
प्रकाशित: (2004)

Therapeutic applications of imino sugars in lysosomal storage disorders.
द्वारा: Butters, T, और अन्य
प्रकाशित: (2003)

Imino sugar therapy for type 1 Gaucher disease.
द्वारा: Priestman, D, और अन्य
प्रकाशित: (2000)

Endoplasmic reticulum targeting liposomes
द्वारा: Pollock, S, और अन्य
प्रकाशित: (2011)

Cholesterol level lowering liposomes
द्वारा: Pollock, S, और अन्य
प्रकाशित: (2012)

Sugar-mediated ligand-receptor interactions in the immune system.
द्वारा: Rudd, P, और अन्य
प्रकाशित: (2004)

The influence of different lipid environments on the structure and function of the hepatitis C virus p7 ion channel protein
द्वारा: Whitfield, T, और अन्य
प्रकाशित: (2011)

The 3-dimensional structure of a hepatitis C virus p7 ion channel by electron microscopy.
द्वारा: Luik, P, और अन्य
प्रकाशित: (2009)

Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: Implications for the development of broad spectrum anti-hepatitis virus agents
द्वारा: Zitzmann, N, और अन्य
प्रकाशित: (1999)

Targeting glycosylation as a therapeutic approach.
द्वारा: Dwek, R, और अन्य
प्रकाशित: (2002)

Prion glycoprotein: structure, dynamics, and roles for the sugars.
द्वारा: Rudd, P, और अन्य
प्रकाशित: (2001)

N-Butyldeoxynojirimycin is a broadly effective anti-HIV therapy significantly enhanced by targeted liposome delivery.
द्वारा: Pollock, S, और अन्य
प्रकाशित: (2008)

Clinical diagnosis of hepatic fibrosis using human serum APOL1 as biomarker
द्वारा: Gangadharan, B, और अन्य
प्रकाशित: (2012)

Clinical diagnosis of hepatic fibrosis using a novel panel of low abundant human plasma protein biomarkers
द्वारा: Gangadharan, B, और अन्य
प्रकाशित: (2010)

Proteomics in uveal melanoma research: opportunities and challenges in biomarker discovery.
द्वारा: Pardo, M, और अन्य
प्रकाशित: (2007)

Clinical diagnosis of hepatic fibrosis using a novel panel of human serum protein biomarkers
द्वारा: Gangadharan, B, और अन्य
प्रकाशित: (2008)

The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.
द्वारा: Bonomelli, C, और अन्य
प्रकाशित: (2011)

Inhibition of glycogen breakdown by imino sugars in vitro and in vivo.
द्वारा: Andersson, U, और अन्य
प्रकाशित: (2004)

Sugar-protein connectivity impacts on the immunogenicity of site-selective salmonella O-antigen glycoconjugate vaccines
द्वारा: Stefanetti, G, और अन्य
प्रकाशित: (2010)

A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120.
द्वारा: Astronomo, R, और अन्य
प्रकाशित: (2008)

Combination therapy for treatment of viral infections
द्वारा: Jeffs, R, और अन्य
प्रकाशित: (2009)

The Hepatitis C Virus E2p7 localization and topology in a recombinant system
द्वारा: Popescu, C, और अन्य
प्रकाशित: (2009)

Iminosugar antivirals: the therapeutic sweet spot
द्वारा: Alonzi, D, और अन्य
प्रकाशित: (2017)

Applying proteomics technology to platelet research.
द्वारा: García, A, और अन्य
प्रकाशित: (2005)

Glycobiology against viruses: Antiviral drug discovery
द्वारा: Zitzmann, N, और अन्य
प्रकाशित: (2006)

Role of N-glycan trimming in the folding and secretion of the pestivirus protein E(rns)
द्वारा: Branza-Nichita, N, और अन्य
प्रकाशित: (2004)

The pestivirus E(rns) glycoprotein interacts with E2 in both infected cells and mature virions.
द्वारा: Lazar, C, और अन्य
प्रकाशित: (2003)

Lysosomal storage of oligosaccharide and glycosphingolipid in imino sugar treated cells.
द्वारा: Boomkamp, S, और अन्य
प्रकाशित: (2010)

Automated glycofingerprinting strategy
द्वारा: Dwek, R, और अन्य
प्रकाशित: (2006)

Novel serum biomarker candidates for liver fibrosis in hepatitis C patients
द्वारा: Gangadharan, B, और अन्य
प्रकाशित: (2007)