Genetic dissection of the α-globin super-enhancer in vivo

Many genes determining cell identity are regulated by clusters of Mediator-bound enhancer elements collectively referred to as super-enhancers. These super-enhancers have been proposed to manifest higher-order properties important in development and disease. Here we report a comprehensive functional...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Hay, D, Hughes, J, Babbs, C, Davies, J, Graham, B, Hanssen, L, Kassouf, M, Oudelaar, A, Sharpe, J, Suciu, M, Telenius, J, Williams, R, Rode, C, Li, P, Pennacchio, L, Sloane-Stanley, J, Ayyub, H, Butler, S, Sauka-Spengler, T, Gibbons, R, Smith, A, Wood, W, Higgs, D
Format:	Journal article
Sprog:	English
Udgivet:	Nature Publishing Group 2016

Genetic dissection of the α-globin super-enhancer in vivo

Lignende værker