Histone deacetylase inhibitors increase virus gene expression but decrease CD8+ cell antiviral function in HTLV-1 infection.

The dynamics of human T-lymphotropic virus type-1 (HTLV-1) provirus expression in vivo are unknown. There is much evidence to suggest that HTLV-1 gene expression is restricted: this restricted gene expression may contribute to HTLV-1 persistence by limiting the ability of the HTLV-1-specific CD8(+)...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Mosley, A, Meekings, K, McCarthy, C, Shepherd, D, Cerundolo, V, Mazitschek, R, Tanaka, Y, Taylor, G, Bangham, C
Format: Journal article
Język:English
Wydane: 2006