Histone deacetylase inhibitors increase virus gene expression but decrease CD8+ cell antiviral function in HTLV-1 infection.

The dynamics of human T-lymphotropic virus type-1 (HTLV-1) provirus expression in vivo are unknown. There is much evidence to suggest that HTLV-1 gene expression is restricted: this restricted gene expression may contribute to HTLV-1 persistence by limiting the ability of the HTLV-1-specific CD8(+)...

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書目詳細資料
Main Authors: Mosley, A, Meekings, K, McCarthy, C, Shepherd, D, Cerundolo, V, Mazitschek, R, Tanaka, Y, Taylor, G, Bangham, C
格式: Journal article
語言:English
出版: 2006