An Arabidopsis Rhomboid homolog is an intramembrane protease in plants.

An Arabidopsis Rhomboid homolog is an intramembrane protease in plants.

Regulated intramembrane proteolysis (RIP) is a fundamental mechanism for controlling a wide range of cellular functions. The Drosophila protein Rhomboid-1 (Rho-1) is an intramembrane serine protease that cleaves epidermal growth factor receptor (EGFR) ligands to release active growth factors. Despit...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Kanaoka, M, Urban, S, Freeman, M, Okada, K
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2005

Eitemau Tebyg

Mechanism and function of the intramembrane-cleaving protease rhomboid
gan: Lemberg, M, et al.
Cyhoeddwyd: (2005)

Mechanism and function of the intramembrane-cleaving protease rhomboid
gan: Lemberg, M, et al.
Cyhoeddwyd: (2005)

Rhomboids and intramembrane proteolysis
gan: Freeman, M, et al.
Cyhoeddwyd: (2005)

Mechanism of intramembrane proteolysis investigated with purified rhomboid proteases.
gan: Lemberg, M, et al.
Cyhoeddwyd: (2005)

Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases.
gan: Urban, S, et al.
Cyhoeddwyd: (2001)

Rhomboid intramembrane proteases: from substrate specificity and mechanism to biological function
gan: Strisovsky, K, et al.
Cyhoeddwyd: (2009)

Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain.
gan: Urban, S, et al.
Cyhoeddwyd: (2003)

Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteases.
gan: Lemberg, M, et al.
Cyhoeddwyd: (2007)

A family of Rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands.
gan: Urban, S, et al.
Cyhoeddwyd: (2002)

Monocyclic β-lactams are selective, mechanism-based inhibitors of rhomboid intramembrane proteases.
gan: Pierrat, O, et al.
Cyhoeddwyd: (2011)

Conservation of intramembrane proteolytic activity and substrate specificity in prokaryotic and eukaryotic rhomboids.
gan: Urban, S, et al.
Cyhoeddwyd: (2002)

Intramembrane proteolysis by rhomboids: catalytic mechanisms and regulatory principles.
gan: Vinothkumar, K, et al.
Cyhoeddwyd: (2013)

Sequence-specific intramembrane proteolysis: identification of a recognition motif in rhomboid substrates.
gan: Strisovsky, K, et al.
Cyhoeddwyd: (2009)

KOMPEITO, an atypical Arabidopsis Rhomboid-related gene, is required for callose accumulation and pollen wall development
gan: Kanaoka, MM, et al.
Cyhoeddwyd: (2022)

Rhomboid intramembrane protease RHBDL4 triggers ER-export and non-canonical secretion of membrane-anchored TGFα
gan: Wunderle, L, et al.
Cyhoeddwyd: (2016)

Rhomboid proteases and their biological functions.
gan: Freeman, M
Cyhoeddwyd: (2008)

Lipid-polymer nanoparticles to probe the native-like environment of intramembrane rhomboid protease GlpG and its activity
gan: Henry Sawczyc, et al.
Cyhoeddwyd: (2024-08-01)

Rhomboid proteases and growth factor signaling
gan: Freeman, M
Cyhoeddwyd: (2009)

Substrates and physiological functions of secretase rhomboids proteases
gan: Freeman, M, et al.
Cyhoeddwyd: (2016)

Rhomboids: 7 years of a new protease family.
gan: Freeman, M
Cyhoeddwyd: (2009)

Rhomboid proteases in human disease: mechanisms and future prospects
gan: Düsterhöft, S, et al.
Cyhoeddwyd: (2017)

Diverse substrate recognition mechanisms for rhomboids; thrombomodulin is cleaved by Mammalian rhomboids.
gan: Lohi, O, et al.
Cyhoeddwyd: (2004)

Signaling Functions of Intramembrane Aspartyl-Proteases
gan: Alkmini A. Papadopoulou, et al.
Cyhoeddwyd: (2020-12-01)

A family of rhomboid-like genes: Drosophila rhomboid-1 and roughoid/rhomboid-3 cooperate to activate EGF receptor signaling.
gan: Wasserman, J, et al.
Cyhoeddwyd: (2000)

Intramembrane-cleaving proteases (I-CLiPs) /
gan: Hooper, Nigel M., et al.
Cyhoeddwyd: (2007)

Mammalian EGF receptor activation by the rhomboid protease RHBDL2.
gan: Adrain, C, et al.
Cyhoeddwyd: (2011)

The structural basis for catalysis and substrate specificity of a rhomboid protease.
gan: Vinothkumar, K, et al.
Cyhoeddwyd: (2010)

Identification of an archaeal presenilin-like intramembrane protease.
gan: Celia Torres-Arancivia, et al.
Cyhoeddwyd: (2010-01-01)

Mitochondrial membrane remodelling regulated by a conserved rhomboid protease.
gan: McQuibban, G, et al.
Cyhoeddwyd: (2003)

Rhomboids.
gan: Freeman, M
Cyhoeddwyd: (2003)

GlyGly-CTERM and rhombosortase: a C-terminal protein processing signal in a many-to-one pairing with a rhomboid family intramembrane serine protease.
gan: Daniel H Haft, et al.
Cyhoeddwyd: (2011-01-01)

Intramembrane proteolysis controls diverse signalling pathways throughout evolution.
gan: Urban, S, et al.
Cyhoeddwyd: (2002)

Structure of rhomboid protease in complex with β-lactam inhibitors defines the S2' cavity.
gan: Vinothkumar, K, et al.
Cyhoeddwyd: (2013)

Bacterial rhomboid proteases mediate quality control of orphan membrane proteins
gan: Liu, G, et al.
Cyhoeddwyd: (2020)

Membrane immersion allows rhomboid proteases to achieve specificity by reading transmembrane segment dynamics
gan: Syed M Moin, et al.
Cyhoeddwyd: (2012-11-01)

Rhomboids, signalling and cell biology
gan: Freeman, M
Cyhoeddwyd: (2016)

The Rip1 intramembrane protease contributes to iron and zinc homeostasis in Mycobacterium tuberculosis
gan: Samantha J. Nelson, et al.
Cyhoeddwyd: (2023-08-01)

Proteolysis within the membrane: rhomboids revealed.
gan: Freeman, M
Cyhoeddwyd: (2004)

Plasmodium vivax rhomboid-like protease 1 gene diversity in Thailand.
gan: Mataradchakul, T, et al.
Cyhoeddwyd: (2017)

Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4
gan: Ikeda, K, et al.
Cyhoeddwyd: (2019)