How can mathematics help us explore vertebrate segmentation?
Since the discovery of gene products oscillating during the formation of vertebral segments, much attention has been directed toward eluciating the molecular basis of the so-called segmentation clock. What research has told us is, that even in the most simple vertebrates, enormously complicated gene...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
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2009
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author | Baker, R Schnell, S |
author_facet | Baker, R Schnell, S |
author_sort | Baker, R |
collection | OXFORD |
description | Since the discovery of gene products oscillating during the formation of vertebral segments, much attention has been directed toward eluciating the molecular basis of the so-called segmentation clock. What research has told us is, that even in the most simple vertebrates, enormously complicated gene networks act in each cell to give rise to oscillations, and that cell-cell communication synchronizes these oscillations between neighboring cells. A number of theories have been proposed to explain both the initiation and maintenance of oscillations in a single cell and the synchronization of such oscillations between cells. We discuss these theories in this Commentary. |
first_indexed | 2024-03-06T23:46:17Z |
format | Journal article |
id | oxford-uuid:710351f8-6995-4b74-aa1c-80db350a382b |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-06T23:46:17Z |
publishDate | 2009 |
record_format | dspace |
spelling | oxford-uuid:710351f8-6995-4b74-aa1c-80db350a382b2022-03-26T19:40:58ZHow can mathematics help us explore vertebrate segmentation?Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:710351f8-6995-4b74-aa1c-80db350a382bEnglishSymplectic Elements at Oxford2009Baker, RSchnell, SSince the discovery of gene products oscillating during the formation of vertebral segments, much attention has been directed toward eluciating the molecular basis of the so-called segmentation clock. What research has told us is, that even in the most simple vertebrates, enormously complicated gene networks act in each cell to give rise to oscillations, and that cell-cell communication synchronizes these oscillations between neighboring cells. A number of theories have been proposed to explain both the initiation and maintenance of oscillations in a single cell and the synchronization of such oscillations between cells. We discuss these theories in this Commentary. |
spellingShingle | Baker, R Schnell, S How can mathematics help us explore vertebrate segmentation? |
title | How can mathematics help us explore vertebrate segmentation? |
title_full | How can mathematics help us explore vertebrate segmentation? |
title_fullStr | How can mathematics help us explore vertebrate segmentation? |
title_full_unstemmed | How can mathematics help us explore vertebrate segmentation? |
title_short | How can mathematics help us explore vertebrate segmentation? |
title_sort | how can mathematics help us explore vertebrate segmentation |
work_keys_str_mv | AT bakerr howcanmathematicshelpusexplorevertebratesegmentation AT schnells howcanmathematicshelpusexplorevertebratesegmentation |