Low-copy-number repeat sequences flank the DiGeorge/velo-cardio-facial syndrome loci at 22q11.
DiGeorge syndrome and velo-cardio-facial syndrome are associated with deletions within 22q11. In attempting to refine the shortest region of overlap for these syndromes we have employed fluorescence in situ hybridisation. The results obtained for some probes indicate the presence of low-copy-number...
| 主要な著者: | , , , , , |
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| フォーマット: | Journal article |
| 言語: | English |
| 出版事項: |
1993
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| _version_ | 1826278597333090304 |
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| author | Halford, S Lindsay, E Nayudu, M Carey, A Baldini, A Scambler, P |
| author_facet | Halford, S Lindsay, E Nayudu, M Carey, A Baldini, A Scambler, P |
| author_sort | Halford, S |
| collection | OXFORD |
| description | DiGeorge syndrome and velo-cardio-facial syndrome are associated with deletions within 22q11. In attempting to refine the shortest region of overlap for these syndromes we have employed fluorescence in situ hybridisation. The results obtained for some probes indicate the presence of low-copy-number repeat families dispersed through proximal 22q. Several primate species have been examined for the presence or absence of two sequences mapping to pter-22q11. The results suggest a relatively recent evolutionary origin for these sequences and the loss of one sequence during the course of primate evolution. |
| first_indexed | 2024-03-06T23:46:18Z |
| format | Journal article |
| id | oxford-uuid:710506be-3f72-4a6b-95b8-0b0e9f220611 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T23:46:18Z |
| publishDate | 1993 |
| record_format | dspace |
| spelling | oxford-uuid:710506be-3f72-4a6b-95b8-0b0e9f2206112022-03-26T19:40:58ZLow-copy-number repeat sequences flank the DiGeorge/velo-cardio-facial syndrome loci at 22q11.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:710506be-3f72-4a6b-95b8-0b0e9f220611EnglishSymplectic Elements at Oxford1993Halford, SLindsay, ENayudu, MCarey, ABaldini, AScambler, PDiGeorge syndrome and velo-cardio-facial syndrome are associated with deletions within 22q11. In attempting to refine the shortest region of overlap for these syndromes we have employed fluorescence in situ hybridisation. The results obtained for some probes indicate the presence of low-copy-number repeat families dispersed through proximal 22q. Several primate species have been examined for the presence or absence of two sequences mapping to pter-22q11. The results suggest a relatively recent evolutionary origin for these sequences and the loss of one sequence during the course of primate evolution. |
| spellingShingle | Halford, S Lindsay, E Nayudu, M Carey, A Baldini, A Scambler, P Low-copy-number repeat sequences flank the DiGeorge/velo-cardio-facial syndrome loci at 22q11. |
| title | Low-copy-number repeat sequences flank the DiGeorge/velo-cardio-facial syndrome loci at 22q11. |
| title_full | Low-copy-number repeat sequences flank the DiGeorge/velo-cardio-facial syndrome loci at 22q11. |
| title_fullStr | Low-copy-number repeat sequences flank the DiGeorge/velo-cardio-facial syndrome loci at 22q11. |
| title_full_unstemmed | Low-copy-number repeat sequences flank the DiGeorge/velo-cardio-facial syndrome loci at 22q11. |
| title_short | Low-copy-number repeat sequences flank the DiGeorge/velo-cardio-facial syndrome loci at 22q11. |
| title_sort | low copy number repeat sequences flank the digeorge velo cardio facial syndrome loci at 22q11 |
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