Conjugation of Folate via Gelonin Carbohydrate Residues Retains Ribosomal-inactivating Properties of the Toxin and Permits Targeting to Folate Receptor Positive Cells

Conjugation of Folate via Gelonin Carbohydrate Residues Retains Ribosomal-inactivating Properties of the Toxin and Permits Targeting to Folate Receptor Positive Cells

<p style="text-align:justify;">Conjugation of folate to proteins permits receptor-mediated endocytosis via the folate receptor (FR) and delivery of the conjugate into the cytoplasm of cells. Since many cancers up-regulate the FR it has enabled the targeting of toxins to tumor cells r...

书目详细资料
Main Authors:	Atkinson, S, Bettinger, T, Seymour, L, Behr, J, Ward, C
格式:	Journal article
出版:	American Society for Biochemistry and Molecular Biology 2001

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