Polyclonal origin of colonic adenomas in an XO/XY patient with FAP.
It is widely accepted that tumors are monoclonal in origin, arising from a mutation or series of mutations in a single cell and its descendants. The clonal origin of colonic adenomas and uninvolved intestinal mucosa from an XO/XY mosaic individual with familial adenomatous polyposis (FAP) was examin...
Main Authors: | Novelli, MR, Williamson, J, Tomlinson, I, Elia, G, Hodgson, S, Talbot, I, Bodmer, W, Wright, N |
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Format: | Journal article |
Language: | English |
Published: |
1996
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