A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein

A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein

Immunization with attenuated Plasmodium falciparum sporozoites (PfSPZs) has been shown to be protective against malaria, but the features of the antibody response induced by this treatment remain unclear. To investigate this response in detail, we isolated IgM and IgG monoclonal antibodies from Tanz...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Tan, J, Sack, B, Oyen, D, Zenklusen, I, Piccoli, L, Barbieri, S, Foglierini, M, Fregni, C, Marcandalli, J, Jongo, S, Abdulla, S, Perez, L, Corradin, G, Varani, L, Sallusto, F, Sim, B, Hoffman, S, Kappe, S, Daubenberger, C, Wilson, I, Lanzavecchia, A
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	Springer Nature 2018

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