Ibudilast inhibits chemokine expression in rheumatoid synovial fibroblasts and exhibits immunomodulatory activity in experimental arthritis
<br/><strong>Objective: </strong>Ibudilast is a well‐tolerated, orally available type 4 phosphodiesterase (PDE4) inhibitor used to treat asthma and stroke. As PDE4 inhibition suppresses inflammatory mediator production and cell proliferation in leukocytes, ibudilast may be a valuab...
Autori principali: | Clanchy, F, Williams, R |
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Natura: | Journal article |
Pubblicazione: |
Wiley
2018
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