The ClC-5 knockout mouse model of Dent's disease has renal hypercalciuria and increased bone turnover.

Dent's disease is a nephrolithiasis disorder associated with hypercalciuria and low molecular weight proteinuria that is caused by mutations in the voltage-gated chloride channel ClC-5. Because the exact cause of hypercalciuria in this disease is unknown and could come from a renal, intestinal,...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Silva, I, Cebotaru, V, Wang, H, Wang, X, Wang, S, Guo, G, Devuyst, O, Thakker, R, Guggino, W, Guggino, SE
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: 2003