The ClC-5 knockout mouse model of Dent's disease has renal hypercalciuria and increased bone turnover.

The ClC-5 knockout mouse model of Dent's disease has renal hypercalciuria and increased bone turnover.

Dent's disease is a nephrolithiasis disorder associated with hypercalciuria and low molecular weight proteinuria that is caused by mutations in the voltage-gated chloride channel ClC-5. Because the exact cause of hypercalciuria in this disease is unknown and could come from a renal, intestinal,...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Silva, I, Cebotaru, V, Wang, H, Wang, X, Wang, S, Guo, G, Devuyst, O, Thakker, R, Guggino, W, Guggino, SE
Format: Journal article
Sprache:English
Veröffentlicht: 2003

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