Lesion load in unprotected carotid artery stenting.

INTRODUCTION: The purpose of the study was to determine the incidence of new ischemic lesions found on diffusion-weighted MR imaging (DWI) in nonselected patients after unprotected carotid artery stent placement. MATERIALS AND METHODS: We retrospectively reviewed a nonrandomized cohort of 197 patie...

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Bibliographic Details
Main Authors: Grunwald, I, Papanagiotou, P, Roth, C, Fassbender, K, Karp, K, Krick, C, Schieber, H, Müller, M, Haass, A, Reith, W
Format: Journal article
Language:English
Published: 2009
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Summary:INTRODUCTION: The purpose of the study was to determine the incidence of new ischemic lesions found on diffusion-weighted MR imaging (DWI) in nonselected patients after unprotected carotid artery stent placement. MATERIALS AND METHODS: We retrospectively reviewed a nonrandomized cohort of 197 patients presenting with carotid occlusive disease who underwent unprotected carotid artery stent placement between 2003 and 2006. Mean degree of stenosis was 86.94% +/- 9.72. In all patients, DWI was obtained before and 24 h after stent placement. New lesions were evaluated according to size and location. RESULTS: In 59 of 197 patients (29.9%), new ischemic lesions were found on DWI in the vessel dependent area. In 23 of 197 patients (11.7%), new ischemic lesions were found in the vessel independent area. Combined stroke/death rate was 3.63%. CONCLUSION: In our series of unprotected carotid angioplasty with stent, we found new DWI lesions in 34% of the patients. Further studies should now show in how far protection devices can reduce these lesions.