Sustained cancer‐relevant alternative RNA splicing events driven by PRMT5 in high‐risk neuroblastoma

Protein arginine methyltransferase 5 (PRMT5) is over‐expressed in a wide variety of cancers and is implicated as having a key oncogenic role, achieved in part through its control of the master transcription regulator E2F1. We investigated the relevance of PRMT5 and E2F1 in neuroblastoma (NB) and fou...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Bate‐Eya, LT, Albayrak, G, Carr, SM, Shrestha, A, Kanapin, A, Samsonova, A, La Thangue, NB
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: Wiley Open Access 2024