Direct Preparation of Heteroaromatic Compounds from Alkenes

A series of aromatic heterocycles, thiazoles, imidazoles, and dimethoxyindoles, can be synthesised directly from alkenes via a ketoiodination-cyclisation protocol. The alkene starting materials are themselves easily accessible by many different and well-established approaches, and allow access to va...

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Bibliographic Details
Main Authors: Donohoe, T, Kabeshov, M, Rathi, A, Smith, I
Format: Journal article
Language:English
Published: 2010
Description
Summary:A series of aromatic heterocycles, thiazoles, imidazoles, and dimethoxyindoles, can be synthesised directly from alkenes via a ketoiodination-cyclisation protocol. The alkene starting materials are themselves easily accessible by many different and well-established approaches, and allow access to various aromatic heterocycles with excellent yields and regioselectivity. © Georg Thieme Verlag Stuttgart - New York.