MEK1/2 blockade by AZD6244 (ARRY-142886) inhibits tumor growth and progression in an orthotopic human lung adenocarcinoma model with enhanced efficacy when combined with cediranib - Takahashi, O; Komaki, R; Smith, P; Ryan, A; Jurgensmeier, J; Welsh, J; Jacoby, J; Hosho, K; Korshunova, M; Erez, B; Herbst, R; O'Reilly, MS (2009)