A selective sweep driven by pyrimethamine treatment in southeast asian malaria parasites.
Malaria parasites (Plasmodium falciparum) provide an excellent system in which to study the genomic effects of strong selection in a recombining eukaryote because the rapid spread of resistance to multiple drugs during the last the past 50 years has been well documented, the full genome sequence and...
Main Authors: | Nair, S, Williams, J, Brockman, A, Paiphun, L, Mayxay, M, Newton, P, Guthmann, J, Smithuis, F, Hien, T, White, N, Nosten, F, Anderson, T |
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格式: | Journal article |
语言: | English |
出版: |
2003
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