A selective sweep driven by pyrimethamine treatment in southeast asian malaria parasites.

Malaria parasites (Plasmodium falciparum) provide an excellent system in which to study the genomic effects of strong selection in a recombining eukaryote because the rapid spread of resistance to multiple drugs during the last the past 50 years has been well documented, the full genome sequence and...

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Main Authors: Nair, S, Williams, J, Brockman, A, Paiphun, L, Mayxay, M, Newton, P, Guthmann, J, Smithuis, F, Hien, T, White, N, Nosten, F, Anderson, T
格式: Journal article
语言:English
出版: 2003