Relative roles of genetic factors, dietary deficiency, and infection in anaemia in Vanuatu, South-West Pacific.
Hypochromic anaemia is very common among the island populations of Vanuatu in the South-West Pacific. Results of a large-scale survey show that, unexpectedly, this form of anaemia is seldom due to iron deficiency or coexistent parasitic disease. Rather, it results from a previously unsuspected high...
| Main Authors: | , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
1985
|
| _version_ | 1797075347190054912 |
|---|---|
| author | Bowden, D Hill, A Higgs, D Weatherall, D Clegg, J |
| author_facet | Bowden, D Hill, A Higgs, D Weatherall, D Clegg, J |
| author_sort | Bowden, D |
| collection | OXFORD |
| description | Hypochromic anaemia is very common among the island populations of Vanuatu in the South-West Pacific. Results of a large-scale survey show that, unexpectedly, this form of anaemia is seldom due to iron deficiency or coexistent parasitic disease. Rather, it results from a previously unsuspected high incidence of alpha-thalassaemia which has been identified only by application of DNA analysis to the populations studied. These findings suggest that hypochromic anaemia in tropical or subtropical populations should not necessarily be attributed to iron deficiency; detailed studies of iron status should be carried out before major dietary changes or fortification of food with iron are implemented. |
| first_indexed | 2024-03-06T23:49:10Z |
| format | Journal article |
| id | oxford-uuid:71ffedd3-ca6d-444c-b54f-ddc08bcc8b9e |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T23:49:10Z |
| publishDate | 1985 |
| record_format | dspace |
| spelling | oxford-uuid:71ffedd3-ca6d-444c-b54f-ddc08bcc8b9e2022-03-26T19:47:18ZRelative roles of genetic factors, dietary deficiency, and infection in anaemia in Vanuatu, South-West Pacific.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:71ffedd3-ca6d-444c-b54f-ddc08bcc8b9eEnglishSymplectic Elements at Oxford1985Bowden, DHill, AHiggs, DWeatherall, DClegg, JHypochromic anaemia is very common among the island populations of Vanuatu in the South-West Pacific. Results of a large-scale survey show that, unexpectedly, this form of anaemia is seldom due to iron deficiency or coexistent parasitic disease. Rather, it results from a previously unsuspected high incidence of alpha-thalassaemia which has been identified only by application of DNA analysis to the populations studied. These findings suggest that hypochromic anaemia in tropical or subtropical populations should not necessarily be attributed to iron deficiency; detailed studies of iron status should be carried out before major dietary changes or fortification of food with iron are implemented. |
| spellingShingle | Bowden, D Hill, A Higgs, D Weatherall, D Clegg, J Relative roles of genetic factors, dietary deficiency, and infection in anaemia in Vanuatu, South-West Pacific. |
| title | Relative roles of genetic factors, dietary deficiency, and infection in anaemia in Vanuatu, South-West Pacific. |
| title_full | Relative roles of genetic factors, dietary deficiency, and infection in anaemia in Vanuatu, South-West Pacific. |
| title_fullStr | Relative roles of genetic factors, dietary deficiency, and infection in anaemia in Vanuatu, South-West Pacific. |
| title_full_unstemmed | Relative roles of genetic factors, dietary deficiency, and infection in anaemia in Vanuatu, South-West Pacific. |
| title_short | Relative roles of genetic factors, dietary deficiency, and infection in anaemia in Vanuatu, South-West Pacific. |
| title_sort | relative roles of genetic factors dietary deficiency and infection in anaemia in vanuatu south west pacific |
| work_keys_str_mv | AT bowdend relativerolesofgeneticfactorsdietarydeficiencyandinfectioninanaemiainvanuatusouthwestpacific AT hilla relativerolesofgeneticfactorsdietarydeficiencyandinfectioninanaemiainvanuatusouthwestpacific AT higgsd relativerolesofgeneticfactorsdietarydeficiencyandinfectioninanaemiainvanuatusouthwestpacific AT weatheralld relativerolesofgeneticfactorsdietarydeficiencyandinfectioninanaemiainvanuatusouthwestpacific AT cleggj relativerolesofgeneticfactorsdietarydeficiencyandinfectioninanaemiainvanuatusouthwestpacific |