Photobleaching reveals complex effects of inhibitors on transcribing RNA polymerase II in living cells.
RNA polymerase II transcribes most eukaryotic genes. Photobleaching studies have revealed that living Chinese hamster ovary cells expressing the catalytic subunit of the polymerase tagged with the green fluorescent protein contain a large rapidly exchanging pool of enzyme, plus a smaller engaged fra...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2007
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