Alpha-tropomyosin mutations in inherited cardiomyopathies.

Alpha-tropomyosin mutations in inherited cardiomyopathies.

The inherited cardiac diseases hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) can both be caused by missense mutations in the TPM1 gene which encodes the thin filament regulatory protein α-tropomyosin. Different mutations are responsible for either HCM or DCM, suggesting that dis...

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Bibliographic Details
Main Authors:	Redwood, C, Robinson, P
Format:	Journal article
Language:	English
Published:	2013

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