Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes

Black women across the African diaspora experience more aggressive breast cancer with higher mortality rates than white women of European ancestry. Although inter-ethnic germline variation is known, differential somatic evolution has not been investigated in detail. Analysis of deep whole genomes of...

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Autors principals:	Ansari-Pour, N, Zheng, Y, Yoshimatsu, TF, Sanni, A, Ajani, M, Reynier, J-B, Tapinos, A, Pitt, JJ, Dentro, S, Woodard, A, Rajagopal, PS, Fitzgerald, D, Gruber, AJ, Odetunde, A, Popoola, A, Falusi, AG, Babalola, CP, Ogundiran, T, Ibrahim, N, Barretina, J, Van Loo, P, Chen, M, White, KP, Ojengbede, O, Obafunwa, J, Huo, D, Wedge, DC, Olopade, OI
Format:	Journal article
Idioma:	English
Publicat:	Springer Nature 2021

Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes

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