A fluorimetric and amperometric study of calcium and secretion in isolated mouse pancreatic beta-cells.

We have examined the temporal relationship between intracellular Ca2+ concentration ([Ca2+]i) and secretion in single intact pancreatic beta-cells. Secretion was detected as the release of 5-hydroxytryptamine from pre-loaded beta-cells, using amperometry, and changes in [Ca2+]i were monitored by mic...

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Bibliographic Details
Main Authors: Smith, P, Duchen, MR, Ashcroft, F
Format: Journal article
Language:English
Published: 1995

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